As well as McCabe has done, I would like to see A. Fainga'a given another opportunity at 12. I think AAC (Adam Ashley-Cooper) can get back some good form at 13 given time and this could be crucial as he is the only player that we have that balances attack and defence. As others have mentioned this also leaves a spot for Mitchell to come back into and with a bit of luck he'll be in form.
As for the horses for courses idea, I am for it. If we were playing the ABs tomorrow I would be quite happy with the current backline and they certainly deserve a chance. However, before his injury was showing a greater willingness to defend with vigor and should be given a chance in the meantime.
In all likelihood someone will get injured and take this discussion away from us, which is great in itself... not the injury part. In 2007 our 1st15 was pretty obvious as there was no one else to step up. We were 1 injury away from failure, which really was the case when Larkham went down. I can't quite remember a player I was disappointed with missing out... except for drew mitchell - common theme me whanging on about him I've realised.