I'm big on building combinations and cohesion, but think we do need a few changes as well. Assuming JOC (James O'Connor), Paisami and LSL (Lukhan Salakaia-Loto) remain unavailable, I would run with:
Slipper, BPA (if fit), Tupou, Swain, Philip, Leota, Hooper, Samu, Tate, Noah, Koroibete, Kerevi, Ikitau, Kellaway, Hodge.
Fainga'a...