The centre pairing has me feeling pretty damn frustrated. For starters, as has been said, they are back to front. Secondly, probably our biggest threats (with the Kerevi omission) would be Kuridrani and CFS. With a 10/12 combo of O'Connor and Fainga'a, they won't even see the ball.
RG said in a press conference mid week (I'm paraphrasing - possibly inaccurately) that our centres were largely dictated by who the Tahs were fielding and what they bring. So I think we can expect to see Ant rushing up all night and trying to nail Beale and start him crabbing. Presumably with Thomson or Gill covering the hole Ant leaves.