With no Benny A, you'd think Sio and Cowan will both now be in the 23. I would still run with Slipper and Kepu to start however. The 2nd row is contentious. I'd run the reds pair to start, but I would do two things as a caveat.
1. I'd say your positions aren't certain lads, work hard or be benched.
2. I'd include both Skelton or Carter and Jones on the bench so they know I'm dead serious (Jones to cover back row). This is ballsy and may need to wait until the second or third test.
the back row largely picks itself (6. Fardy, 7. Hooper and 8. Cliff).
9. Genia 10. Foley
12. To'omua 13. AAC (Adam Ashley-Cooper) (I see why you would put him on the wing, but at this point is time he's just the best option plain and simple)
11. Badge 14. One of Horne or McCabe (not fussed)
15. Izzy
TPN, Sio, Cowan (cover tight head?), Skelton, Jones (higgers if necessary), White, Beale and the other one out of Horne/McCabe.