Forgetting that performance against the Baabaas - because it means precisely zero for England's chances out here - we need to think about set piece first and foremost, and how we're going to blunt England's forwards.
There are more lineouts than scrums in a game, so while we need to focus on being solid in getting the ball out on the deck, having enough targets at 4, 5, and 6 on the throw will be more important.
The back row therefore comes down to balance. Particularly against England with Itoje roaming around as a lock who plays like a blindside. You need someone who is an utter fluffybunny to get in his face all day and take him out of play as often as possible. Someone like Scott Fardy who wouldn't put up with Itoje's off-the-ball shit.
I think Holloway deserves a shot at lock based on his form through the season. There are plenty of other options, but I see him as the Brad Thorn style hard man who does the dirty work then shows up to give a nice ball to the winger. Team him up with a bigger guy like one of the Ponies' locks (except Swain who is a fucking penalty magnet despite all his good stuff) and you're getting there for a pack.
For me, Valetini is your blockbuster 8 running the hard lines, with Hooper a lock at 7. Samu is the ultimate bench cover.
Therefore, blindside is last man standing for selection in that pack. Is Wilson a better option at 6 compared to the other guys available? Will his attributes balance a likely pack of Slipper, Porecki, Ala'alatoa, Holloway, Another, Hooper, and Valetini?
Looking at the options, probably "yes"