I would have no lineout concerns if we pick Wright and Samu. They are for lineout purposes extra locks. I think Wright has the most lineout steals in the comp, and is an exceptional lineout target.
I personally would have the back row something like Samu, Wright, Willson or Wright, McReight, Samu (anticipating McReight continuing on his current trajectory). With Hooper & Willson/Isi on the bench. I REALLY think with so many other back rowers playing so very well I think we can't justify Hooper's limited skill set and fairly average form being in the XV. Plus he's basically purpose built for coming off the bench.
I think the bench should be a 6/2 split given our backline should have an abundance of guys who can play anywhere. And we will probably need to test out a few locks.
I agree with those who have said Isi is too one dimensional and even in that one dimension he's not exceptionally ahead of the much more dynamic Willson for example.
I'd also mention (again) Andrew Ready as a hooking option. In terms of scrum/lineout/maul he's probably our most complete all around option plus he's very handy around the park. Maybe BPA could be a better option because he'd probably fit our overall balance a little better given he's very good in that wider channel (obviously you could change the back row to fix that). I'm not sure how much of FF (Folau Fainga'a) is him and how much is the system he's playing in. Also I have never rated Uelelse, until he actually has some Super Rugby or test form (he's never had any kind of form), at best he's coming off the bench.
As for Fullback, I agree conventional wisdom will be to pick DHP or Hodge. I'd say if DHP isn't starting at XV he's not in the 23 because he only really plays fullback, whereas Hodge play... anything after 9. For those who think Campbell is ready then throw him in for a game. But I'd sooner start Banks -- I personally think the thing that seals it for me is his kicking for touch off penalties, he's got a canon for a boot and is a specialist touch finder. Maddocks hasn't been consistently good enough IMO, extended squad probably, but I'd be hard pressed to have him in my 23.
Not sure what people think about the Locks?