The Wallabies have a lot of issues to overcome before they will be able to compete with England.
The scrum is generally very good, but if they have to bring Ainsley on for any length of time, I expect England will have a run of scrum penalties and some late penalty goal kicking opportunities.
I think our backrow will again struggle against a bigger and more aggressive trio in England, though Hooper will be more effective playing a proper No 7 position in the absence of Pocock. A lot will depend on how Dempsey is shaping up. He really hasn't been near his best in the last couple of tests. Not a lot of good ball carrying ability across Hooper, Samu and and out of form Dempsey, while Pocock will be sorely missed for his turnover capabilities when under pressure.
The lineout is likely to be a problem. Latu's throwing has been the poorest of the hookers on tour, and his propensity to do stupid things could well see him YCed at some stage. Again, with a smallish trio in the backrow, the England jumpers will probably have a field day.
The defense in the back line is probably the biggest worry. Can't see Foley defending at 12 against the likes of Teo and Tuilagi, so the swapping of positions will likely be retained with the added fatigue for the outside backs and Genia running all over the place will become a factor again. And if Foley plays with ball in hand like he did against Italy, there is little hope of the Wallabies getting over the gain line or through the defensive line to get into scoring positions.
The lack of real pace out wide with DHP and Folau will also mitigate against the Wallabies being able to put tries on the board.
All in all, if England play to their abilities and to a reasonable game plan, they are well in the hunt to put a sizeable score on the Wallabies tonight.